NEUTROPHILS EXPRESSING PROGRAMMED DEATH-LIGAND 1 PLAY AN INDISPENSABLE ROLE IN EFFECTIVE BACTERIAL ELIMINATION AND RESOLVING INFLAMMATION IN METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS INFECTION

Programmed death ligand 1 (PD-L1) is a co-inhibitory molecule expressed on the surface of various cell types and known for its suppressive effect on T cells through its interaction with PD-1.Neutrophils also express PD-L1, and its N/A expression is elevated in specific situations; however, the immunobiological role of PD-L1+ neutrophils has not bee

Context: Although the number of people with physical disabilities who need nursing support is increasing, there is a lack of empirical knowledge about how they experience necessary care support.This knowledge is a prerequisite for enabling self-determination in the provision of care and for providing care based on needs and requirements.People with

Protein glycosylation is one of the most common and most important post-translational modifications.Despite the growing knowledge on N-glycosylation, the research on O-glycosylation is lagging behind.This study investigates the importance of O-glycosylation in the post-embryonic development of insects using the red flour beetle, Tribolium castaneum

Prion diseases are sub-acute neurodegenerative diseases that affect humans and some domestic and free-ranging animals.Infectious prion agents are considered to comprise solely of abnormally folded isoforms of the cellular prion protein known as PrPSc.Pathology during prion disease CARDIO FLOW is restricted to the central nervous system where it cau